Acanthosis nigricans - Acantose Nigricans
☆ Nos resultados do Stiftung Warentest de 2022 da Alemanha, a satisfação do consumidor com o ModelDerm foi apenas ligeiramente inferior do que com as consultas pagas de telemedicina.
É comum em pessoas obesas.
References
Acanthosis nigricans é uma manifestação cutânea de uma doença subjacente. Muitas vezes aparece em dobras cutâneas como pescoço, axilas e virilha, parecendo manchas escuras aveludadas com bordas pouco nítidas. Essa condição geralmente está associada ao diabetes e à resistência à insulina, mas, em casos raros, pode indicar câncer no corpo. Também pode aparecer devido a problemas hormonais ou ao tomar medicamentos específicos, como esteróides e pílulas anticoncepcionais.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans is a cutaneous manifestation of an underlying condition. It usually develops in skin folds, such as the back of the neck, axilla, and groin, where it presents as velvety hyper-pigmented patches with poorly defined borders. Acanthosis nigricans is most commonly associated with diabetes and insulin resistance, but rarely it can be a sign of internal malignancy. It can also occur with hormone disorders or with the use of certain medications like systemic glucocorticoids and oral contraceptives.
Acanthosis nigricans (AN) é uma doença de pele comum associada a vários problemas de saúde, como resistência à insulina, diabetes, obesidade, certos tipos de câncer, problemas hormonais e reações a medicamentos. O tratamento da AN concentra-se na abordagem dos problemas de saúde subjacentes. Inicialmente, os médicos verificam sinais de síndrome de resistência à insulina, que inclui obesidade, colesterol alto, pressão alta e diabetes tipo 2. Os médicos geralmente prescrevem topical retinoids como primeira opção de tratamento, o que pode ajudar no espessamento da pele. No entanto, eles podem não resolver totalmente o escurecimento da pele. Outras opções de tratamento como salicylic acid, podophyllin, urea, and calcipotriol também precisam de aplicação frequente.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
Acanthosis nigricans (AN) is a common dermatologic manifestation of systemic disease that is associated with insulin resistance, diabetes mellitus, obesity, internal malignancy, endocrine disorders, and drug reactions. Treatment of AN primarily focuses on resolution of the underlying disease processes causing the velvety, hyperpigmented, hyperkeratotic plaques found on the skin. Initial considerations for the AN workup include evaluating patients for insulin resistance syndrome characterized by obesity, dyslipidemia, hypertension, and diabetes mellitus type II. For cosmetic treatment, topical retinoids are considered the first-line therapy for insulin-resistant AN by modifying keratinization rate. However, topical tretinoin requires application for long durations and improves hyperkeratosis, but not hyperpigmentation. Topical salicylic acid, podophyllin, urea, and calcipotriol also require frequent application, while TCA peels may provide a faster and less time-intense burden.
○ Causas
Geralmente ocorre em indivíduos com menos de 40 anos, pode ser herdada geneticamente e está associada à obesidade ou endocrinopatias, como hipotireoidismo, acromegalia, doença dos ovários policísticos, diabetes resistente à insulina ou doença de Cushing.
○ Tratamento - Medicamentos OTC
#40% urea cream